Colofac IBS Relief 135mg – 15 Tablets

Description

Colofac IBS Relief 135mg – 15 Tablets

Colofac IBS Relief 135mg tablets contain mebeverine hydrochloride, an antispasmodic medicine used to relieve the painful and uncomfortable symptoms of irritable bowel syndrome (IBS), including stomach cramps, bloating, and changes in bowel habits.

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How It Works

Mebeverine hydrochloride works by relaxing the smooth muscle in the wall of the gut. This helps to reduce painful spasms and cramps without affecting normal bowel movement, easing discomfort associated with IBS.

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Directions for Use

Adults and children aged 10 years and over: Take one tablet (135mg) three times a day, preferably 20 minutes before meals. Swallow the tablets whole with water. Do not exceed the recommended dose. This medicine is not recommended for children under 10 years of age. Always read the patient information leaflet before use. If you are unsure about the correct dose, speak to your PillSorted pharmacist.

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Active Ingredients

• Mebeverine hydrochloride 135mg per tablet

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Possible Side Effects

Colofac IBS Relief is generally well tolerated. Side effects are uncommon but may include:
• Allergic reactions such as skin rash, hives, or itching
• Swelling of the face, lips, or throat (angioedema — rare)
• Facial flushing (rare)

If you experience any serious side effects, stop taking this medicine and seek medical advice immediately.

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Who Should Not Take This Medicine

• People who are allergic to mebeverine hydrochloride or any of the other ingredients
• Children under 10 years of age
• People with a rare inherited condition called porphyria
• People with paralytic ileus (a condition where the bowel stops working)

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Interactions

There are no well-documented interactions between mebeverine and other medicines. However, as with all medicines, it is important to let your healthcare provider know what you are taking. Tell your PillSorted pharmacist or doctor about all medicines you are currently taking, including herbal remedies and supplements.

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Pregnancy and Breastfeeding

The safety of mebeverine during pregnancy and breastfeeding has not been fully established. It is not recommended for use during pregnancy or whilst breastfeeding unless advised by a doctor. Speak to your doctor or PillSorted pharmacist before use if you are pregnant, trying to conceive, or breastfeeding.

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Alcohol

There is no known interaction between mebeverine hydrochloride and alcohol. However, alcohol can irritate the gut and may worsen IBS symptoms, so it is advisable to drink in moderation when managing IBS.

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Driving and Operating Machinery

Colofac IBS Relief is not known to cause drowsiness or affect alertness. It is not expected to impair your ability to drive or operate machinery. However, if you feel unwell after taking this medicine, exercise caution.

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Storage

Store below 25°C in a dry place, away from direct sunlight. Keep out of sight and reach of children. Do not use after the expiry date shown on the packaging.

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Important Information

• This product is a medicine. Speak to your doctor or PillSorted pharmacist before taking this product if you have an underlying medical condition or are taking any other medication or complementary therapy.
• If symptoms worsen or persist, contact your doctor.
• If pregnant, trying to conceive or breastfeeding, seek medical advice before use.
• If you suffer from allergies, confirm suitability with your PillSorted pharmacist before use.
• Store out of sight and reach of children.
• Read the enclosed patient information leaflet carefully before use.
• Contact your GP where appropriate.

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Patient Information Leaflet

For the full Patient Information Leaflet (PIL) for this medicine, visit the electronic Medicines Compendium (EMC). For further information about this medicine, visit NHS.uk.

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This content has been medically reviewed and approved by Zeinab Ardeshir (GPhC 2075730), Superintendent Pharmacist at PillSorted (GPhC-registered online pharmacy 9011258). Last reviewed: February 2026.

Brand	COLOFAC