Calpol SixPlus Sugar Free 5ml – 12 Sachets

Description

Calpol SixPlus Sugar Free 5ml – 12 Sachets

Calpol SixPlus Sugar Free sachets are a children’s medicine suitable for ages 6 and over, used to relieve mild to moderate pain — such as headaches, toothache, and sore throats — and to reduce fever. Each sachet contains a pre-measured 5ml dose of sugar-free paracetamol suspension, making it a convenient option for children who have difficulty swallowing tablets.

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How It Works

The active ingredient, paracetamol, works by blocking the production of certain chemicals in the body called prostaglandins, which are responsible for causing pain and raising body temperature. By reducing prostaglandin levels, paracetamol helps to relieve discomfort and bring a high temperature down to a more normal level.

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Directions for Use

Calpol SixPlus Sugar Free is for children aged 6 to 12 years. Each sachet contains one 5ml dose (250mg paracetamol). The recommended doses are as follows:

• Children aged 6–8 years: 5ml (1 sachet) per dose
• Children aged 8–10 years: 7.5ml (1.5 sachets) per dose
• Children aged 10–12 years: 10ml (2 sachets) per dose

Doses may be given up to 4 times in 24 hours, leaving at least 4 hours between doses. Do not give more than 4 doses in any 24-hour period. Do not give this medicine to a child for more than 3 days without speaking to a doctor. Always read the patient information leaflet before use. If you are unsure about the correct dose, speak to your PillSorted pharmacist.

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Active Ingredients

• Paracetamol 250mg per 5ml sachet

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Possible Side Effects

Calpol SixPlus Sugar Free is generally well tolerated when used as directed. Side effects are uncommon but may include:

• Allergic reactions such as skin rash or itching
• Nausea or stomach upset
• Low blood platelet count (very rare, associated with paracetamol)
• Liver or kidney problems (rare, usually associated with overdose or prolonged use)

If you experience any serious side effects, stop taking this medicine and seek medical advice immediately.

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Who Should Not Take This Medicine

Do not give this medicine to a child who:

• Is allergic to paracetamol or any other ingredient in this product
• Is under 6 years of age
• Has severe liver or kidney problems
• Is already taking another medicine containing paracetamol (to avoid exceeding the maximum daily dose)
• Has been advised by a doctor not to take paracetamol

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Interactions

Paracetamol can interact with certain medicines, including blood-thinning medicines such as warfarin, medicines used to treat epilepsy (e.g. carbamazepine, phenytoin), and some antibiotics such as chloramphenicol. Taking other products containing paracetamol at the same time can lead to an overdose. Tell your PillSorted pharmacist or doctor about all medicines you are currently taking, including herbal remedies and supplements.

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Pregnancy and Breastfeeding

This medicine is intended for children aged 6 to 12 years and is not indicated for use in adults, including those who are pregnant or breastfeeding. If a parent or carer is pregnant or breastfeeding and requires paracetamol for themselves, they should seek separate advice. Speak to your doctor or PillSorted pharmacist before use if you are pregnant, trying to conceive, or breastfeeding.

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Alcohol

This medicine is intended for children, so alcohol consumption is not applicable to the patient. Parents and carers should ensure this medicine is stored safely and used only as directed for the child.

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Driving and Operating Machinery

Calpol SixPlus Sugar Free does not contain any ingredients known to cause drowsiness, and it is not expected to affect a child’s ability to carry out normal activities. If a child seems unusually drowsy after taking this medicine, seek medical advice.

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Storage

Store below 25°C in a dry place. Do not refrigerate or freeze. Once a sachet has been opened, the contents should be used immediately and any unused portion discarded. Keep out of sight and reach of children. Do not use after the expiry date shown on the packaging.

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Important Information

• This product is a medicine. Speak to your doctor or PillSorted pharmacist before taking this product if you have an underlying medical condition or are taking any other medication or complementary therapy.
• If symptoms worsen or persist, contact your doctor.
• If pregnant, trying to conceive or breastfeeding, seek medical advice before use.
• If you suffer from allergies, confirm suitability with your PillSorted pharmacist before use.
• Store out of sight and reach of children.
• Read the enclosed patient information leaflet carefully before use.
• Contact your GP where appropriate.

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Patient Information Leaflet

For the full Patient Information Leaflet (PIL) for this medicine, visit the electronic Medicines Compendium (EMC). For further information about this medicine, visit NHS.uk.

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This content has been medically reviewed and approved by Zeinab Ardeshir (GPhC 2075730), Superintendent Pharmacist at PillSorted (GPhC-registered online pharmacy 9011258). Last reviewed: February 2026.

Brand	Calpol