Maloff Protect 250mg/100mg – 24 Tablets

Description

Maloff Protect 250mg/100mg Tablets – 24tablet 2 X – 12tablets

Maloff Protect contains two active ingredients — atovaquone and proguanil hydrochloride — and is used to prevent malaria in adults and children weighing 40 kg or more travelling to areas where malaria is present. It can also be used to treat malaria caused by Plasmodium falciparum.

⸻

How It Works

Atovaquone and proguanil work together to kill the malaria parasite at different stages of its life cycle. Atovaquone disrupts the parasite’s ability to produce energy, while proguanil interferes with its ability to reproduce. Together, they provide effective protection against the most common and dangerous form of malaria.

⸻

Directions for Use

For prevention of malaria in adults and children over 40 kg: take one tablet once daily. Start taking the tablets 1–2 days before entering the malaria risk area, continue throughout your stay, and for 7 days after leaving the area. Tablets should be taken at the same time each day with food or a milky drink to help absorption. If you vomit within one hour of taking a tablet, take another one as soon as possible. Always read the patient information leaflet before use. If you are unsure about the correct dose, speak to your PillSorted pharmacist.

⸻

Active Ingredients

• Atovaquone 250 mg per tablet
• Proguanil hydrochloride 100 mg per tablet

⸻

Possible Side Effects

• Headache
• Nausea or vomiting
• Stomach pain or diarrhoea
• Dizziness
• Vivid or unusual dreams
• Loss of appetite
• Skin rash or itching
• Mouth ulcers

If you experience any serious side effects, stop taking this medicine and seek medical advice immediately.

⸻

Who Should Not Take This Medicine

• People with a known allergy to atovaquone, proguanil, or any other ingredient in the tablet
• People with severe kidney problems (creatinine clearance less than 30 mL/min) — unless using for treatment under medical supervision
• Children weighing less than 40 kg (for this adult-strength tablet)
• People who are already being treated for malaria with this medicine

⸻

Interactions

Maloff Protect may interact with the following medicines, which can reduce its effectiveness or increase the risk of side effects:
• Rifampicin or rifabutin (antibiotics)
• Metoclopramide (used for nausea)
• Tetracycline antibiotics
• Warfarin and other anticoagulants (blood-thinning medicines)
• Indinavir (used for HIV)

Tell your PillSorted pharmacist or doctor about all medicines you are currently taking, including herbal remedies and supplements.

⸻

Pregnancy and Breastfeeding

Maloff Protect is not recommended during pregnancy unless the benefit is considered to outweigh the risk, as there is limited safety data available. It should not be taken whilst breastfeeding, as proguanil passes into breast milk and its effects on a nursing infant are not fully established. Speak to your doctor or PillSorted pharmacist before use if you are pregnant, trying to conceive, or breastfeeding.

⸻

Alcohol

There is no specific interaction between Maloff Protect and alcohol; however, drinking alcohol may worsen some of the gastrointestinal side effects such as nausea and stomach discomfort. It is advisable to drink alcohol in moderation while taking this medicine.

⸻

Driving and Operating Machinery

Maloff Protect may cause dizziness in some people, which could affect your ability to drive or operate machinery safely. If you feel dizzy or unwell after taking this medicine, do not drive or use machinery until you feel better.

⸻

Storage

Store below 25°C in a dry place, away from direct sunlight and heat. Keep the tablets in their original packaging to protect them from moisture. Keep out of sight and reach of children. Do not use after the expiry date shown on the packaging.

⸻

Important Information

• This product is a medicine. Speak to your doctor or PillSorted pharmacist before taking this product if you have an underlying medical condition or are taking any other medication or complementary therapy.
• If symptoms worsen or persist, contact your doctor.
• If pregnant, trying to conceive or breastfeeding, seek medical advice before use.
• If you suffer from allergies, confirm suitability with your PillSorted pharmacist before use.
• Store out of sight and reach of children.
• Read the enclosed patient information leaflet carefully before use.
• Contact your GP where appropriate.

⸻

Patient Information Leaflet

For the full Patient Information Leaflet (PIL) for this medicine, visit the electronic Medicines Compendium (EMC). For further information about this medicine, visit NHS.uk.

⸻

This content has been medically reviewed and approved by Zeinab Ardeshir (GPhC 2075730), Superintendent Pharmacist at PillSorted (GPhC-registered online pharmacy 9011258). Last reviewed: March 2026.

Brand	Maloff
Class	Pharmacy Medicine