Maloff Protect 250mg/100mg – 36 Tablets

Description

Maloff Protect 250mg/100mg Tablets – 36tablet 3 X – 12tablets

Maloff Protect contains two active ingredients, atovaquone and proguanil hydrochloride, and is used to prevent malaria in adults and children weighing 40kg or more. It is taken before, during, and after travel to areas where malaria is a risk.

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How It Works

Maloff Protect works by combining two medicines that attack the malaria parasite in different ways. Atovaquone disrupts the parasite’s ability to produce energy, while proguanil interferes with its ability to reproduce. Together, they work to prevent the malaria parasite from surviving and multiplying in your body.

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Directions for Use

The usual adult dose is one tablet taken once daily with food or a milky drink. Start taking the tablets 1–2 days before entering a malaria risk area, continue every day whilst in the area, and for 7 days after returning. The tablets should be taken at the same time each day. This pack contains 36 tablets (3 x 12 tablets), providing a 36-day supply for one adult. Always read the patient information leaflet before use. If you are unsure about the correct dose, speak to your PillSorted pharmacist.

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Active Ingredients

• Atovaquone 250mg per tablet
• Proguanil hydrochloride 100mg per tablet

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Possible Side Effects

• Headache
• Nausea or feeling sick
• Stomach pain or discomfort
• Vomiting
• Diarrhoea
• Dizziness
• Vivid or unusual dreams
• Mouth ulcers

If you experience any serious side effects, stop taking this medicine and seek medical advice immediately.

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Who Should Not Take This Medicine

• People who are allergic to atovaquone, proguanil hydrochloride, or any other ingredient in the tablet
• People with severe kidney problems
• Children weighing less than 40kg (a different strength is available for smaller children)
• People who have previously had a serious reaction to this type of medicine

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Interactions

Maloff Protect may interact with several medicines, including rifampicin or rifabutin (antibiotics), metoclopramide (used for nausea), warfarin and other anticoagulants (blood thinners), and tetracycline antibiotics. Some medicines can reduce the effectiveness of Maloff Protect, so it is important to check all current medications before starting this treatment. Tell your PillSorted pharmacist or doctor about all medicines you are currently taking, including herbal remedies and supplements.

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Pregnancy and Breastfeeding

Maloff Protect is not recommended during pregnancy unless the benefit outweighs the risk, as there is limited safety data available. It is also not recommended whilst breastfeeding, as the ingredients may pass into breast milk. Speak to your doctor or PillSorted pharmacist before use if you are pregnant, trying to conceive, or breastfeeding.

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Alcohol

There is no specific interaction between Maloff Protect and alcohol. However, drinking alcohol may worsen side effects such as nausea, dizziness, or headache, so it is advisable to drink in moderation whilst taking this medicine.

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Driving and Operating Machinery

Maloff Protect may cause dizziness in some people. If you feel dizzy or lightheaded after taking this medicine, do not drive or operate machinery until you feel well again. Most people are not affected and can continue normal activities.

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Storage

Store below 25°C in a dry place, away from direct sunlight and heat. Keep the tablets in their original blister packaging until you need them. Keep out of sight and reach of children. Do not use after the expiry date shown on the packaging.

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Important Information

• This product is a medicine. Speak to your doctor or PillSorted pharmacist before taking this product if you have an underlying medical condition or are taking any other medication or complementary therapy.
• If symptoms worsen or persist, contact your doctor.
• If pregnant, trying to conceive or breastfeeding, seek medical advice before use.
• If you suffer from allergies, confirm suitability with your PillSorted pharmacist before use.
• Store out of sight and reach of children.
• Read the enclosed patient information leaflet carefully before use.
• Contact your GP where appropriate.

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Patient Information Leaflet

For the full Patient Information Leaflet (PIL) for this medicine, visit the electronic Medicines Compendium (EMC). For further information about this medicine, visit NHS.uk.

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This content has been medically reviewed and approved by Zeinab Ardeshir (GPhC 2075730), Superintendent Pharmacist at PillSorted (GPhC-registered online pharmacy 9011258). Last reviewed: March 2026.

Brand	Maloff
Class	Pharmacy Medicine