Gina 10mg Vaginal Tablets – 24 Pack

Description

Gina 10mg Vaginal Tablets – 24 Pack

Gina 10mg Vaginal Tablets are a local hormone replacement therapy (HRT) used to relieve vaginal symptoms of the menopause, such as dryness, itching, burning, and discomfort during sex. They contain estradiol, a form of oestrogen, and are available without a prescription for women aged 50 and over who have not had a period for at least one year.

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How It Works

During and after the menopause, oestrogen levels in the body fall, which can cause the lining of the vagina to become thinner, drier, and less elastic. Each Gina tablet is inserted directly into the vagina, where it releases a small amount of estradiol locally to help restore and maintain the vaginal lining, relieving dryness and irritation without significantly raising oestrogen levels in the rest of the body.

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Directions for Use

Gina 10mg Vaginal Tablets are for use in women aged 50 and over who have not had a period for at least one year. One tablet is inserted into the vagina once daily for the first two weeks (the initial treatment period), then one tablet is inserted twice weekly (every 3 to 4 days) as a maintenance dose. Each tablet comes with an applicator to help with insertion. Treatment should be reviewed after 24 weeks (approximately 6 months). Always read the patient information leaflet before use. If you are unsure about the correct dose, speak to your PillSorted pharmacist.

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Active Ingredients

• Estradiol hemihydrate 10.3mcg (equivalent to estradiol 10mcg) per vaginal tablet

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Possible Side Effects

• Vaginal discharge or spotting
• Vaginal discomfort, irritation, or itching
• Pelvic pain or pressure
• Breast tenderness or pain
• Headache
• Nausea
• Urinary tract infections (UTIs)
• Abnormal vaginal bleeding

If you experience any serious side effects, stop taking this medicine and seek medical advice immediately.

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Who Should Not Take This Medicine

• Women under 50 years of age
• Women who have had a period within the last 12 months
• Women who are pregnant or breastfeeding
• Women with known, suspected, or a history of breast cancer
• Women with known or suspected oestrogen-dependent cancers (e.g. endometrial cancer)
• Women with unexplained vaginal bleeding
• Women with a history of or current blood clots (deep vein thrombosis or pulmonary embolism)
• Women with known allergy to estradiol or any other ingredient in the tablet
• Women with severe liver disease

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Interactions

Because Gina delivers oestrogen locally to the vagina with very little absorption into the bloodstream, clinically significant interactions with other medicines are unlikely at the recommended dose. However, medicines that affect liver enzymes — such as certain anticonvulsants (e.g. carbamazepine, phenytoin), antibiotics (e.g. rifampicin), and herbal remedies such as St John’s Wort — may theoretically affect how oestrogen is processed in the body. Tell your PillSorted pharmacist or doctor about all medicines you are currently taking, including herbal remedies and supplements.

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Pregnancy and Breastfeeding

Gina 10mg Vaginal Tablets are not intended for use during pregnancy or whilst breastfeeding, and should only be used by women who have gone through the menopause. If there is any possibility you could be pregnant, do not use this product. Speak to your doctor or PillSorted pharmacist before use if you are pregnant, trying to conceive, or breastfeeding.

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Alcohol

There is no known direct interaction between Gina 10mg Vaginal Tablets and alcohol. However, drinking alcohol regularly can affect oestrogen levels in the body and may increase certain risks associated with HRT, so it is advisable to keep alcohol consumption within recommended guidelines.

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Driving and Operating Machinery

Gina 10mg Vaginal Tablets are not known to affect your ability to drive or operate machinery. If you experience any unexpected side effects that affect your alertness or concentration, seek medical advice before driving.

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Storage

Store Gina 10mg Vaginal Tablets below 25°C in a dry place, away from direct heat and sunlight. Keep the tablets in their original packaging until ready to use. Keep out of sight and reach of children. Do not use after the expiry date shown on the packaging.

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Important Information

• This product is a medicine. Speak to your doctor or PillSorted pharmacist before taking this product if you have an underlying medical condition or are taking any other medication or complementary therapy.
• If symptoms worsen or persist, contact your doctor.
• If pregnant, trying to conceive or breastfeeding, seek medical advice before use.
• If you suffer from allergies, confirm suitability with your PillSorted pharmacist before use.
• Store out of sight and reach of children.
• Read the enclosed patient information leaflet carefully before use.
• Contact your GP where appropriate.

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Patient Information Leaflet

For the full Patient Information Leaflet (PIL) for this medicine, visit the electronic Medicines Compendium (EMC). For further information about this medicine, visit NHS.uk.

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This content has been medically reviewed and approved by Zeinab Ardeshir (GPhC 2075730), Superintendent Pharmacist at PillSorted (GPhC-registered online pharmacy 9011258). Last reviewed: February 2026.

Brand	Gina