E45 Itch Relief Cream – 100g

£7.10

In Stock

E45 Itch Relief Cream is a soothing, non-greasy cream used to relieve itching and irritation associated with dry skin conditions such as eczema, dermatitis, and other itchy skin complaints. It is suitable for adults and children aged 3 years and over.

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    Description

    E45 Itch Relief Cream – 100g

    E45 Itch Relief Cream is a soothing, non-greasy cream used to relieve itching and irritation associated with dry skin conditions such as eczema, dermatitis, and other itchy skin complaints. It is suitable for adults and children aged 3 years and over.

    How It Works

    The active ingredient, lauromacrogols (also known as macrogol lauryl ether), works by calming the nerve endings in the skin that cause the sensation of itch. It has a mild local anaesthetic effect on the skin’s surface, reducing the urge to scratch while also helping to soothe and moisturise the affected area.

    Directions for Use

    Apply a thin layer of cream to the affected area and gently rub in. This can be done up to three times daily, or as often as needed to relieve itching. For adults and children aged 3 years and over. Do not apply to broken or infected skin. Always read the patient information leaflet before use. If you are unsure about the correct dose, speak to your PillSorted pharmacist.

    Active Ingredients

    • Lauromacrogols (Macrogol Lauryl Ether) 3% w/w

    Possible Side Effects

    Most people use this cream without experiencing any side effects. However, some people may notice:
    • Mild skin irritation or redness at the site of application
    • Burning or stinging sensation on application
    • Skin rash or allergic reaction (rare)
    • Worsening of skin irritation (rare)

    If you experience any serious side effects, stop taking this medicine and seek medical advice immediately.

    Who Should Not Take This Medicine

    • People who are allergic to lauromacrogols or any other ingredient in the cream
    • Children under 3 years of age
    • Do not apply to broken, weeping, or infected skin
    • Do not apply near the eyes or mucous membranes
    • Do not use on areas of skin that are severely inflamed without first consulting a doctor

    Interactions

    E45 Itch Relief Cream is applied to the skin and is not expected to interact with other medicines taken by mouth. However, avoid using alongside other topical skin preparations on the same area at the same time without seeking advice first. Tell your PillSorted pharmacist or doctor about all medicines you are currently taking, including herbal remedies and supplements.

    Pregnancy and Breastfeeding

    There is limited information on the use of lauromacrogols during pregnancy or breastfeeding. As a precaution, avoid applying the cream to the breast area if breastfeeding. Speak to your doctor or PillSorted pharmacist before use if you are pregnant, trying to conceive, or breastfeeding.

    Alcohol

    There is no known interaction between E45 Itch Relief Cream and alcohol. This product is applied topically to the skin and is not taken by mouth, so alcohol consumption is not expected to affect how it works.

    Driving and Operating Machinery

    E45 Itch Relief Cream is applied to the skin and is not expected to affect your ability to drive or operate machinery. It does not cause drowsiness or any other effects that would impair alertness.

    Storage

    Store below 25°C in a dry place, away from direct sunlight and heat. Do not freeze. Keep out of sight and reach of children. Do not use after the expiry date shown on the packaging.

    Important Information

    • This product is a medicine. Speak to your doctor or PillSorted pharmacist before taking this product if you have an underlying medical condition or are taking any other medication or complementary therapy.
    • If symptoms worsen or persist, contact your doctor.
    • If pregnant, trying to conceive or breastfeeding, seek medical advice before use.
    • If you suffer from allergies, confirm suitability with your PillSorted pharmacist before use.
    • Store out of sight and reach of children.
    • Read the enclosed patient information leaflet carefully before use.
    • Contact your GP where appropriate.

    Patient Information Leaflet

    For the full Patient Information Leaflet (PIL) for this medicine, visit the electronic Medicines Compendium (EMC). For further information about this medicine, visit NHS.uk.

    This content has been medically reviewed and approved by Zeinab Ardeshir (GPhC 2075730), Superintendent Pharmacist at PillSorted (GPhC-registered online pharmacy 9011258). Last reviewed: February 2026.

    Brand

    E45