
E45 Dermatological Cream – 50g
£3.20
Ship in 1-3 days
E45 Dermatological Cream is a trusted, gentle moisturiser used to relieve and soothe dry, itchy, flaky, chapped, rough, and calloused skin, as well as sunburn. It is suitable for the whole family, including babies, and is specially formulated for sensitive skin.
Description
E45 Dermatological Cream – 50g
E45 Dermatological Cream is a trusted, gentle moisturiser used to relieve and soothe dry, itchy, flaky, chapped, rough, and calloused skin, as well as sunburn. It is suitable for the whole family, including babies, and is specially formulated for sensitive skin.
⸻
How It Works
E45 Cream contains emollient ingredients — white soft paraffin, light liquid paraffin, and anhydrous lanolin — that work together to form a protective layer on the surface of the skin. This barrier helps lock in the skin’s natural moisture and prevents further water loss, keeping skin soft, hydrated, and comfortable.
⸻
Directions for Use
Apply E45 Cream to the affected area of skin as often as needed, smoothing it in gently. It can be used on the face, hands, and body, and is safe for regular, long-term use. It is suitable for adults, children, and babies. Always read the patient information leaflet before use. If you are unsure about the correct dose, speak to your PillSorted pharmacist.
⸻
Active Ingredients
• White Soft Paraffin 14.5% w/w
• Light Liquid Paraffin 12.6% w/w
• Anhydrous Lanolin (Hypoallergenic) 1% w/w
⸻
Possible Side Effects
E45 Cream is generally very well tolerated. However, some people may experience:
• Skin irritation or redness at the site of application
• Allergic skin reactions, such as a rash or itching
• Sensitivity reactions to lanolin (wool fat) in rare cases
• Folliculitis (inflammation of hair follicles) with prolonged heavy use
If you experience any serious side effects, stop taking this medicine and seek medical advice immediately.
⸻
Who Should Not Take This Medicine
• People who are allergic to white soft paraffin, light liquid paraffin, anhydrous lanolin, or any other ingredient in the cream
• People with a known sensitivity or allergy to wool fat (lanolin)
• Do not apply to broken, infected, or heavily inflamed skin without first seeking medical advice
⸻
Interactions
E45 Cream is applied to the skin and is not known to interact with other medicines when used as directed. However, as with all emollient products, it is advisable to avoid applying other topical preparations to exactly the same area at the same time without guidance. Tell your PillSorted pharmacist or doctor about all medicines you are currently taking, including herbal remedies and supplements.
⸻
Pregnancy and Breastfeeding
E45 Cream is generally considered suitable for use during pregnancy and breastfeeding, as it is applied to the skin and is not absorbed into the bloodstream in significant amounts. If using on the breast or nipple area while breastfeeding, ensure the cream is removed before feeding your baby. Speak to your doctor or PillSorted pharmacist before use if you are pregnant, trying to conceive, or breastfeeding.
⸻
Alcohol
There is no known interaction between E45 Dermatological Cream and alcohol. This product is applied to the skin and does not interact with alcohol consumption.
⸻
Driving and Operating Machinery
E45 Cream does not affect your ability to drive or operate machinery. It is a topical product and has no effect on alertness or concentration.
⸻
Storage
Store E45 Dermatological Cream below 25°C in a dry place, away from direct heat and sunlight. Keep the lid tightly closed when not in use. Keep out of sight and reach of children. Do not use after the expiry date shown on the packaging.
⸻
Important Information
• This product is a medicine. Speak to your doctor or PillSorted pharmacist before taking this product if you have an underlying medical condition or are taking any other medication or complementary therapy.
• If symptoms worsen or persist, contact your doctor.
• If pregnant, trying to conceive or breastfeeding, seek medical advice before use.
• If you suffer from allergies, confirm suitability with your PillSorted pharmacist before use.
• Store out of sight and reach of children.
• Read the enclosed patient information leaflet carefully before use.
• Contact your GP where appropriate.
⸻
Patient Information Leaflet
For the full Patient Information Leaflet (PIL) for this medicine, visit the electronic Medicines Compendium (EMC). For further information about this medicine, visit NHS.uk.
⸻
This content has been medically reviewed and approved by Zeinab Ardeshir (GPhC 2075730), Superintendent Pharmacist at PillSorted (GPhC-registered online pharmacy 9011258). Last reviewed: February 2026.
| Weight | 1 kg |
|---|---|
| Brand | E45 |


























