You’ve Done It! What Happens Next?
Congratulations on reaching your target weight! 🎉 We know how much hard work has gone into this, and we’re genuinely thrilled for you. Beyond the number on the scales, you’ve likely noticed health improvements too — steadier blood sugar levels, healthier blood pressure, and an overall boost in wellbeing.
But now a big question naturally comes up: “How do I keep this weight off?” Don’t worry — you’re not alone. Just as we’ve supported you on your weight loss journey, we’ll be right by your side as you move into maintenance.
The Reality of Weight Maintenance
Here’s something important that isn’t often said: obesity is a chronic condition. Like high blood pressure or diabetes, it usually requires ongoing management.
Just as someone with high blood pressure continues taking their medication even when their readings normalise, many people find they need to stay on their GLP-1 medication alongside their healthy lifestyle changes to maintain their results.
This isn’t a failure or weakness – it’s simply how these medications work with your body’s natural systems.

What Actually Happens If You Stop Taking Mounjaro (Tirzepatide)?
We’re not trying to scare you, but it’s important you know the facts. There was a study called SURMOUNT-4 that looked at exactly this question.
In the trial, people who’d reached a stable weight on tirzepatide were split into two groups. Half continued their medication, whilst the other half unknowingly switched to a placebo injection. Over the following year, those who stopped the active medication regained about 14% of their weight, whilst those who stayed on tirzepatide lost another 5.5%.
The key takeaway? The medication is doing important work in your body, and stopping it can lead to weight regain.

Your Maintenance Options: The Pillsorted Maintenance Programme
Every person is different, and what works brilliantly for your neighbour might not be right for you. At PillSorted, our clinicians tailor a plan that fits your needs and lifestyle. There are three main approaches:
1. Continue Your Current Dose
This is the gold standard method and the most widely studied. If your current dose keeps your weight stable and controls appetite, there’s no reason to change.
2. Find Your Lowest Effective Dose
Some patients prefer to see if they can maintain results with less. For example, stepping down from 10mg to 7.5mg while monitoring weight and appetite. If the lower dose works, great — if not, we can increase again.
3. Gradually Taper Off
For those who want to try lifestyle maintenance without medication, we’ll reduce the dose slowly over months. This helps the body adjust and lowers the risk of rapid weight regain. If you need to restart later, we’ll safely build the dose back up.
Important note: If you pause GLP-1 treatment and decide to restart, you’ll need to begin at a lower dose and gradually build back up. This is the safest approach.
How We’ll Support You Through This
- At BMI 26: We’ll reach out to start planning your personalised maintenance strategy.

- At BMI 25: You’ll join our maintenance programme, with more frequent check-ins (every 4 weeks) than during weight loss.
We’ll monitor your progress, adjust your plan if needed, and provide the ongoing support you deserve.
The Most Important Thing to Remember
Your journey with us doesn’t end when you reach your goal weight. In many ways, it’s just beginning! We’re committed to supporting you for as long as you need us, whether that’s months or years. You’ve worked incredibly hard to get here, and we’re going to make sure you have every tool and bit of support you need to maintain these fantastic results.
Remember, there’s no “one size fits all” when it comes to maintenance. What matters is finding the approach that works for you, fits into your life, and keeps you feeling confident and healthy. We’re here to figure that out together.
Frequently Asked Questions
Will I need to stay on GLP-1 medication forever?
Not necessarily. Some people continue long term because it helps them maintain their results, while others can reduce their dose or gradually stop. The right plan depends on your body, your progress, and your goals.
What happens if I stop taking Mounjaro or Wegovy?
Clinical trials show that many people regain weight after stopping suddenly. That’s because these medicines help regulate appetite and metabolism. If you decide to stop, it’s safest to reduce your dose gradually under medical supervision.
Can I restart treatment if I’ve taken a break?
Yes. But you won’t be able to jump straight back to your previous dose. For safety, you’ll need to restart at a lower dose and build up again.
Is it possible to maintain my weight without medication?
For some people, yes. A healthy lifestyle with balanced eating, regular activity, and close monitoring can be enough. But many find that staying on some level of medication helps keep appetite and cravings under control.
How often will I check in with PillSorted during maintenance?
Once your BMI reaches 25, you’ll move onto our maintenance programme. We’ll check in every four weeks to make sure your plan is working and adjust if needed.
Is it normal to feel anxious about keeping the weight off?
Absolutely. Reaching your goal weight is a big achievement, and it’s natural to worry about the next phase. The good news is you’re not alone — our team will support you with a personalised strategy to help you feel confident and in control.
Related
- Bloating from GLP-1 Injections
- Common GLP-1 Weight-loss Side Effects
- Constipation from GLP-1 Injections
- Dehydration from GLP-1 Injections
- Diarrhoea from GLP-1 Injections
- Dry Mouth from GLP-1 Injections
- Injectable Weight Loss Treatments (GLP-1)
- Nausea & Vomiting from GLP-1 Injections
- Sulphur Burps from GLP-1 Injections
- Obesity
- Weight Loss