Nytol Liquid Caramel Flavour 10mg/5ml – 300ml

Description

Nytol Liquid Caramel Flavour 10mg/5ml Oral Solution – 300ml

Nytol Liquid Caramel Flavour is a sleep aid designed for adults who are experiencing temporary difficulty sleeping (insomnia). It contains the antihistamine diphenhydramine hydrochloride, which helps you fall asleep more easily on occasions when you have trouble getting to sleep.

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How It Works

Diphenhydramine hydrochloride is an antihistamine that causes drowsiness as a side effect of blocking histamine receptors in the brain. By reducing brain activity associated with wakefulness, it helps you feel sleepy and fall asleep more quickly. It is intended for short-term use only and is not suitable for long-term management of sleep problems.

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Directions for Use

Adults and young people aged 16 and over should take 20ml (containing 40mg of diphenhydramine hydrochloride) in a single dose, 20 minutes before going to bed. Use the measuring cup provided to measure the correct dose. Do not take more than one dose in 24 hours, and do not use for more than two consecutive weeks without speaking to a doctor. Always read the patient information leaflet before use. If you are unsure about the correct dose, speak to your PillSorted pharmacist.

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Active Ingredients

• Diphenhydramine hydrochloride 10mg per 5ml (40mg per 20ml dose)

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Possible Side Effects

• Drowsiness or sedation the following day
• Dry mouth, nose, or throat
• Blurred vision
• Difficulty passing urine
• Headache
• Nausea or upset stomach
• Dizziness

If you experience any serious side effects, stop taking this medicine and seek medical advice immediately.

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Who Should Not Take This Medicine

• Children under 16 years of age
• People who are allergic to diphenhydramine or any other ingredient in this product
• People with glaucoma (increased pressure in the eye)
• People with difficulty passing urine (such as those with an enlarged prostate)
• People with epilepsy
• People with chronic bronchitis, asthma, or other breathing problems
• People taking monoamine oxidase inhibitors (MAOIs) or who have taken them within the last 14 days
• People with liver or kidney problems (unless advised by a doctor)

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Interactions

Nytol Liquid may interact with other medicines that cause drowsiness, including certain antidepressants, antipsychotics, sedatives, anxiety medicines, and other antihistamines. It may also interact with medicines used to treat Parkinson’s disease (such as anticholinergics), and some medicines used for stomach problems. Taking diphenhydramine with monoamine oxidase inhibitors (MAOIs) is particularly dangerous and must be avoided. Tell your PillSorted pharmacist or doctor about all medicines you are currently taking, including herbal remedies and supplements.

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Pregnancy and Breastfeeding

Nytol Liquid is not recommended during pregnancy as diphenhydramine may have effects on the developing baby, particularly near the time of delivery. Diphenhydramine can pass into breast milk and may cause sedation in a breastfed infant, so it should not be used while breastfeeding. Speak to your doctor or PillSorted pharmacist before use if you are pregnant, trying to conceive, or breastfeeding.

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Alcohol

You must not drink alcohol while taking Nytol Liquid. Alcohol significantly increases the sedative effect of diphenhydramine, which can lead to excessive drowsiness and may impair your breathing and reflexes. Avoid alcohol completely on any day you take this medicine.

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Driving and Operating Machinery

Nytol Liquid causes drowsiness, and this effect may continue into the following morning. Do not drive, cycle, or operate machinery after taking this medicine, and ensure you allow sufficient time to sleep before needing to be alert. If you feel drowsy or dizzy the next day, you must not drive or operate heavy machinery.

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Storage

Store below 25°C in a dry place, away from direct sunlight and heat. Once opened, refer to the patient information leaflet for guidance on the shelf life of the product. Keep out of sight and reach of children. Do not use after the expiry date shown on the packaging.

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Important Information

• This product is a medicine. Speak to your doctor or PillSorted pharmacist before taking this product if you have an underlying medical condition or are taking any other medication or complementary therapy.
• If symptoms worsen or persist, contact your doctor.
• If pregnant, trying to conceive or breastfeeding, seek medical advice before use.
• If you suffer from allergies, confirm suitability with your PillSorted pharmacist before use.
• Store out of sight and reach of children.
• Read the enclosed patient information leaflet carefully before use.
• Contact your GP where appropriate.

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Patient Information Leaflet

For the full Patient Information Leaflet (PIL) for this medicine, visit the electronic Medicines Compendium (EMC). For further information about this medicine, visit NHS.uk.

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This content has been medically reviewed and approved by Zeinab Ardeshir (GPhC 2075730), Superintendent Pharmacist at PillSorted (GPhC-registered online pharmacy 9011258). Last reviewed: March 2026.

Brand	Nytol
Class	Pharmacy Medicine