
HC45 Cream 1% w/w – 15g
£5.49
Ship in 1-3 days
HC45 Cream 1% w/w contains hydrocortisone acetate, a mild topical corticosteroid used to relieve itching, redness, and inflammation caused by conditions such as mild to moderate eczema, insect bites, contact dermatitis (including detergent hands), nickel allergy, and plant allergy.
Description
HC45 Cream 1% w/w – 15g
HC45 Cream 1% w/w contains hydrocortisone acetate, a mild topical corticosteroid used to relieve itching, redness, and inflammation caused by conditions such as mild to moderate eczema, insect bites, contact dermatitis (including detergent hands), nickel allergy, and plant allergy.
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How It Works
Hydrocortisone acetate belongs to a group of medicines called corticosteroids. It works by calming the immune response in the skin that causes redness, swelling, and itching, helping to reduce inflammation and provide relief to irritated or inflamed skin.
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Directions for Use
For adults and children aged 10 years and over, apply a thin layer of cream to the affected area once or twice daily. Do not use for more than 7 days without seeking medical advice, and avoid applying to the face unless directed by a doctor. Do not cover the treated area with an airtight dressing unless advised by your doctor. Always read the patient information leaflet before use. If you are unsure about the correct dose, speak to your PillSorted pharmacist.
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Active Ingredients
• Hydrocortisone Acetate 1% w/w (equivalent to 10 mg per gram of cream)
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Possible Side Effects
• Skin thinning with prolonged use
• Burning, stinging, or irritation at the application site
• Skin discolouration or changes in pigmentation
• Stretch marks (striae), particularly with long-term use
• Increased hair growth at the application site
• Allergic skin reactions (rash, redness, or worsening of symptoms)
If you experience any serious side effects, stop taking this medicine and seek medical advice immediately.
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Who Should Not Take This Medicine
• Children under 10 years of age (without medical supervision)
• People with a known allergy to hydrocortisone acetate or any other ingredient in the cream
• Those with skin infections caused by bacteria, viruses, or fungi (e.g., ringworm, impetigo, cold sores, chickenpox)
• People with acne, rosacea, or perioral dermatitis
• Do not apply to broken, infected, or weeping skin
• Do not use around the eyes or on large areas of the body without medical advice
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Interactions
HC45 Cream is applied to the skin and is not expected to cause significant interactions with other medicines when used as directed. However, using other topical products on the same area of skin at the same time may affect absorption. Tell your PillSorted pharmacist or doctor about all medicines you are currently taking, including herbal remedies and supplements.
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Pregnancy and Breastfeeding
The use of topical hydrocortisone during pregnancy and breastfeeding should be kept to a minimum. If breastfeeding, avoid applying the cream to the breast or nipple area to prevent the baby coming into contact with it. Speak to your doctor or PillSorted pharmacist before use if you are pregnant, trying to conceive, or breastfeeding.
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Alcohol
There is no known interaction between HC45 Cream and alcohol. This medicine is applied to the skin and is not taken orally, so alcohol consumption is not expected to affect its safety or effectiveness.
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Driving and Operating Machinery
HC45 Cream is a topical product and is not expected to affect your ability to drive or operate machinery. If you experience any unexpected side effects that affect your alertness, take caution and seek advice from your PillSorted pharmacist.
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Storage
Store below 25°C in a dry place, away from direct heat and sunlight. Do not refrigerate or freeze. Keep out of sight and reach of children. Do not use after the expiry date shown on the packaging.
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Important Information
• This product is a medicine. Speak to your doctor or PillSorted pharmacist before taking this product if you have an underlying medical condition or are taking any other medication or complementary therapy.
• If symptoms worsen or persist, contact your doctor.
• If pregnant, trying to conceive or breastfeeding, seek medical advice before use.
• If you suffer from allergies, confirm suitability with your PillSorted pharmacist before use.
• Store out of sight and reach of children.
• Read the enclosed patient information leaflet carefully before use.
• Contact your GP where appropriate.
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Patient Information Leaflet
For the full Patient Information Leaflet (PIL) for this medicine, visit the electronic Medicines Compendium (EMC). For further information about this medicine, visit NHS.uk.
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This content has been medically reviewed and approved by Zeinab Ardeshir (GPhC 2075730), Superintendent Pharmacist at PillSorted (GPhC-registered online pharmacy 9011258). Last reviewed: February 2026.
| Weight | 0.02 kg |
|---|---|
| Brand | HC45 |


























