Difflam 3mg Orange & Honey – 20 Lozenges

Description

Difflam 3mg Orange & Honey – 20 Lozenges

Difflam 3mg Orange & Honey Lozenges are used to relieve the pain and discomfort of a sore throat. Each lozenge contains benzydamine hydrochloride, a non-steroidal anti-inflammatory drug (NSAID), and is available in a pleasant orange and honey flavour.

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How It Works

Benzydamine hydrochloride works by reducing inflammation and numbing the tissues in your throat, helping to relieve pain and soreness. It acts locally in the mouth and throat, so it gets to work directly where it is needed without being significantly absorbed into the rest of the body.

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Directions for Use

Adults and children aged 6 years and over: dissolve one lozenge slowly in the mouth every 1.5 to 3 hours as needed, up to a maximum of 8 lozenges in 24 hours. Children aged 6 to 12 years should use no more than 4 lozenges in 24 hours. The lozenges should be sucked slowly and not chewed or swallowed whole. Always read the patient information leaflet before use. If you are unsure about the correct dose, speak to your PillSorted pharmacist.

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Active Ingredients

• Benzydamine hydrochloride 3mg per lozenge

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Possible Side Effects

• Numbness or tingling in the mouth or throat
• Dry mouth
• Nausea
• Hypersensitivity reactions such as skin rash or itching
• Rarely, allergic reactions including swelling of the face, lips, or throat (angioedema)

If you experience any serious side effects, stop taking this medicine and seek medical advice immediately.

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Who Should Not Take This Medicine

• Children under 6 years of age
• Anyone with a known allergy to benzydamine hydrochloride or any other ingredient in the product
• People with phenylketonuria (these lozenges contain aspartame)
• Anyone with a known intolerance to certain sugars — check the full ingredient list with your PillSorted pharmacist
• Those who have previously had an allergic reaction (such as asthma, hives, or swelling) after taking aspirin or other NSAIDs

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Interactions

No significant interactions with other medicines have been identified for benzydamine hydrochloride used as a lozenge, as it acts locally in the mouth and throat with minimal systemic absorption. However, if you are taking other medicines — particularly other NSAIDs or aspirin — it is always best to check. Tell your PillSorted pharmacist or doctor about all medicines you are currently taking, including herbal remedies and supplements.

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Pregnancy and Breastfeeding

The use of Difflam lozenges is not recommended during pregnancy, particularly during the third trimester, as NSAIDs may affect the unborn baby. There is insufficient data on the use of benzydamine during breastfeeding, so caution is advised. Speak to your doctor or PillSorted pharmacist before use if you are pregnant, trying to conceive, or breastfeeding.

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Alcohol

There is no known significant interaction between Difflam lozenges and alcohol. However, alcohol can irritate an already sore or inflamed throat and may worsen your symptoms, so it is best to avoid alcohol while you are experiencing throat discomfort.

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Driving and Operating Machinery

Difflam lozenges are not expected to affect your ability to drive or operate machinery. However, if you experience any unusual effects such as dizziness after using these lozenges, do not drive or operate machinery and speak to your PillSorted pharmacist.

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Storage

Store below 25°C in a dry place, away from direct sunlight and heat. Keep out of sight and reach of children. Do not use after the expiry date shown on the packaging.

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Important Information

• This product is a medicine. Speak to your doctor or PillSorted pharmacist before taking this product if you have an underlying medical condition or are taking any other medication or complementary therapy.
• If symptoms worsen or persist, contact your doctor.
• If pregnant, trying to conceive or breastfeeding, seek medical advice before use.
• If you suffer from allergies, confirm suitability with your PillSorted pharmacist before use.
• Store out of sight and reach of children.
• Read the enclosed patient information leaflet carefully before use.
• Contact your GP where appropriate.

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Patient Information Leaflet

For the full Patient Information Leaflet (PIL) for this medicine, visit the electronic Medicines Compendium (EMC). For further information about this medicine, visit NHS.uk.

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This content has been medically reviewed and approved by Zeinab Ardeshir (GPhC 2075730), Superintendent Pharmacist at PillSorted (GPhC-registered online pharmacy 9011258). Last reviewed: February 2026.

Brand	DIFFLAM