Clotrimazole Cream 1% – 50g (Brand May Vary)

Description

Clotrimazole Cream 1% – 50g (Brand May Vary)

Clotrimazole Cream 1% is an antifungal cream used to treat fungal skin infections such as athlete’s foot (tinea pedis), ringworm (tinea corporis), fungal nappy rash, and candidal skin infections including those affecting the groin, armpits, and skin folds.

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How It Works

Clotrimazole belongs to a group of medicines called azole antifungals. It works by disrupting the outer membrane (cell wall) of the fungus, causing the contents to leak out and killing the fungus. This stops the infection from spreading and helps to clear up the symptoms of redness, itching, and irritation.

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Directions for Use

Adults and children aged 12 and over: Apply a thin layer of cream to the affected area and the skin immediately surrounding it, 2–3 times a day. Gently rub the cream in. Continue using the cream for 2–4 weeks, even if the symptoms improve, to ensure the infection has fully cleared. For athlete’s foot, it is especially important to continue treatment for at least 4 weeks. This cream is for external use on the skin only — do not use inside the vagina or mouth. Always read the patient information leaflet before use. If you are unsure about the correct dose, speak to your PillSorted pharmacist.

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Active Ingredients

• Clotrimazole 10 mg per gram (1% w/w)

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Possible Side Effects

• Mild burning, stinging, or irritation at the site of application
• Skin redness or rash
• Itching or peeling of the skin
• Blistering or swelling at the application site
• Allergic skin reaction (hypersensitivity) — uncommon but possible

If you experience any serious side effects, stop taking this medicine and seek medical advice immediately.

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Who Should Not Take This Medicine

• People with a known allergy to clotrimazole or any other ingredient in the cream
• People with a known allergy to other azole antifungals (e.g. miconazole, fluconazole)
• Children under 12 years of age (unless directed by a doctor)
• Do not use in or around the eyes
• Do not use inside the vagina (a separate vaginal formulation should be used for vaginal thrush)

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Interactions

Clotrimazole cream is applied to the skin and is not significantly absorbed into the bloodstream, so interactions with other medicines are unlikely. However, if you are using latex contraceptives (condoms or diaphragms) in the genital area, the cream may weaken the latex and reduce their effectiveness — use an alternative method of contraception during treatment in these circumstances. Tell your PillSorted pharmacist or doctor about all medicines you are currently taking, including herbal remedies and supplements.

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Pregnancy and Breastfeeding

Clotrimazole cream is generally considered safe for use during pregnancy and breastfeeding when applied to the skin. However, during the first trimester of pregnancy in particular, it is advisable to use it only when necessary and under medical guidance. If applying to the breast area, ensure the cream is thoroughly washed off before breastfeeding. Speak to your doctor or PillSorted pharmacist before use if you are pregnant, trying to conceive, or breastfeeding.

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Alcohol

There is no known interaction between clotrimazole cream and alcohol. Drinking alcohol does not affect how this cream works, as it is applied topically to the skin and is not significantly absorbed into the bloodstream.

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Driving and Operating Machinery

Clotrimazole cream is applied to the skin and is not expected to affect your ability to drive or operate machinery. No special precautions are required in this regard.

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Storage

Store below 25°C in a dry place, away from direct heat and sunlight. Do not refrigerate or freeze the cream. Keep out of sight and reach of children. Do not use after the expiry date shown on the packaging.

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Important Information

• This product is a medicine. Speak to your doctor or PillSorted pharmacist before taking this product if you have an underlying medical condition or are taking any other medication or complementary therapy.
• If symptoms worsen or persist, contact your doctor.
• If pregnant, trying to conceive or breastfeeding, seek medical advice before use.
• If you suffer from allergies, confirm suitability with your PillSorted pharmacist before use.
• Store out of sight and reach of children.
• Read the enclosed patient information leaflet carefully before use.
• Contact your GP where appropriate.

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Patient Information Leaflet

For the full Patient Information Leaflet (PIL) for this medicine, visit the electronic Medicines Compendium (EMC). For further information about this medicine, visit NHS.uk.

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This content has been medically reviewed and approved by Zeinab Ardeshir (GPhC 2075730), Superintendent Pharmacist at PillSorted (GPhC-registered online pharmacy 9011258). Last reviewed: March 2026.

Brand	Generic
Class	Pharmacy Medicine