Omeprazole

Omeprazole (Losec) is a proton pump inhibitor (PPI) for acid reflux. Strengths, how to take it, side effects, FAQs, and how to get it delivered free on the NHS with PillSorted.

Omeprazole is a commonly prescribed medicine in the UK, used for acid reflux. If you have just been prescribed omeprazole, this page explains what it is, the brands and strengths it comes in, how to take it, and how to have it dispensed and delivered free on the NHS with PillSorted.

This content has been medically reviewed and approved by Zeinab Ardeshir (GPhC 2075730), Superintendent Pharmacist at PillSorted (GPhC-registered online pharmacy 9011258). Last reviewed: 2 July 2026.

What is omeprazole?

Omeprazole is a proton pump inhibitor (PPI) that reduces the amount of acid your stomach makes. It is used for acid reflux, heartburn and stomach ulcers.

Brands and strengths

Omeprazole is the name of the active ingredient. In the UK it is sold as generic omeprazole and under brand names including Losec, Mepradec and Pyrocalm — all contain the same active ingredient and work the same way. Common strengths:

  • Omeprazole 10 mg tablets
  • Omeprazole 20 mg tablets
  • Omeprazole 40 mg tablets
  • UK brands: Losec, Mepradec and Pyrocalm

What omeprazole is used for

  • Acid reflux and heartburn (GORD)
  • Stomach and duodenal ulcers
  • Protecting the stomach on certain medicines

How to take omeprazole

Usually taken once a day, before food (often in the morning). Swallow capsules whole with water. Always follow your prescriber’s instructions (BNF).

Side effects

Common effects include headache, wind, diarrhoea or constipation and feeling sick, which often settle. This is not a full list — see the patient information leaflet (BNF).

Omeprazole: frequently asked questions

Is omeprazole the same as Losec?

Yes. Losec is the original brand name for omeprazole; the generic is the same active ingredient.

When should I take omeprazole?

Usually once a day before food. Taking it before breakfast works well for most people.

Can I get omeprazole delivered free on the NHS with PillSorted?

Yes. If you have an NHS prescription for omeprazole, you can nominate PillSorted as your NHS pharmacy and we will dispense and deliver it to your door for free.


Get your omeprazole delivered free on the NHS

If you have an NHS prescription for omeprazole, PillSorted dispenses and delivers it to your door — completely free. Nominate PillSorted as your NHS pharmacy once, and we take care of your repeat prescriptions from then on.

What you get

  • Free delivery, every time — your medicine posted to your door, always free.
  • Your whole family, one account — manage everyone’s prescriptions in one place.
  • Real pharmacists, every prescription — every order checked by our UK pharmacist team.

How it works

  1. Choose PillSorted as your NHS pharmacy
  2. We collect your prescription from your GP
  3. Your medication is delivered free to your door

Sources: NICE; BNF — Omeprazole.

This page is for general information only and is not a substitute for advice from your GP or pharmacist. Always take your medicine exactly as prescribed. For advice about your own health, consult a clinician.

PillSorted is an NHS full-service pharmacy that delivers.